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Breathe Easy: How Nebulizers are Transforming Asthma Care

  • Farhana Khan Sara
  • Oct 5, 2024
  • 4 min read

Author: Farhana Khan Sara


Asthma, also known as Bronchial Asthma, is a chronic illness that causes difficulties in breathing,

wheezing, and persistent coughing, which is, affecting millions of people worldwide (including more than

25 million people in the U.S. currently, and, in total, more than 5 million children).


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What is a Nebulizer?


A Nebulizer is a medical device that changes medication from a liquid to a mist, making it easier to inhale

directly into the lungs. It is asked to be frequently used for the treatments, of Asthma, Cystic Fibrosis,

COPD, and other respiratory diseases or disorders. A Nebulizer uses oxygen, compressed air, or

ultrasonic power to break up solutions and suspensions into small aerosol (mixture of gas and solid or

liquid particles) droplets inspired by the gadget's mouthpiece. Nebulizers include - Jet Nebulizers, Soft

Mist Inhalers, Ultrasonic Wave Nebulizers, and Vibrating Mesh Technology.


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Nebulizer Type 01 - Jet Nebulizer


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Nebulizer Type 02 - Soft Mist Inhaler


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Nebulizer Type 03 - Ultrasonic Wave Nebulizer


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Nebulizer Type 04 - Vibrating Mesh Technology (Nebulizer)





Historical Evolution of Nebulizers


● The history of inhalation devices begins with Sales-Girons' pressurized inhaler in France (1858),

which atomized liquid medication using a bicycle pump-like mechanism. In 1864, Germany

introduced Siegle's steam spray inhaler, a nebulizer that, used steam and the Venturi principle to

atomize medications, although, its efficacy was limited due to a lack of understanding of droplet

size.


● The 1930s saw the advent of the Pneumostat, an electrically driven nebulizer, alongside the

simpler hand-driven Parke-Davis Glaseptic. In 1956, Riker Laboratories launched the first

pressurized metered-dose inhalers, using gas propellants like Freon to deliver precise doses of

medication.


● The 1964 introduction of ultrasonic wave nebulizers marked a technological shift, which later

found applications in humidifiers and electronic cigarettes. Early e-cigarettes employed ultrasonic


nebulization but have since transitioned to more efficient electric vaporizers that utilize

atomization techniques, optimizing nicotine delivery.


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Medications Used in a Nebulizer


● Bronchodilators

➔ Albuterol (Salbutamol): Short-acting beta-agonist (SABA) for quick relief of asthma

symptoms.

➔ Levalbuterol: Another SABA, often used for patients who experience side effects from

albuterol.

➔ Ipratropium Bromide: An anticholinergic bronchodilator, often used in combination

with other medications.


● Corticosteroids

➔ Budesonide: Used for long-term control of asthma and reducing inflammation.

➔ Fluticasone: Another inhaled corticosteroid to help manage asthma symptoms.


● Combination Medications

➔ Budesonide/Formoterol: A combination of a corticosteroid and a long-acting

beta-agonist (LABA).

➔ Albuterol/Ipratropium: Combines a SABA with an anticholinergic for enhanced

bronchodilation.


● Mucolytics

➔ Acetylcysteine: Helps to thin mucus, making it easier to cough up, often used in

conditions like cystic fibrosis.


● Antibiotics

➔ Tobramycin: An inhaled antibiotic used to treat lung infections, particularly in patients

with cystic fibrosis.


● Leukotriene Modifiers (not typically nebulized but relevant for asthma management)

➔ Montelukast: Taken orally but sometimes considered in overall asthma management.


● Others


➔ Pentamidine: Used for certain types of pneumonia, particularly in immunocompromised

patients.





Ways of Using It and Attachments


Nebulizers deliver liquid medication, typically corticosteroids and bronchodilators like salbutamol,

directly to the respiratory tract for faster effects and fewer side effects. Patients usually use a mouthpiece,

but face masks can be used for children and the elderly. After using corticosteroids, rinsing the mouth is

recommended to reduce the risk of oral thrush or hoarseness. While bronchodilators don’t carry the same

risks, rinsing can help with unpleasant tastes.


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Benefits and Drawbacks of Using a Nebulizer


In conclusion, nebulizers represent a vital advancement in the management of asthma and other

respiratory conditions, offering a range of benefits that enhance patient care. Their ability to deliver

medication directly to the lungs, ease of use for individuals of all ages, and versatility in treating various

respiratory diseases make them an invaluable tool for both acute relief and long-term management. As

technology continues to evolve, nebulizers are likely to become even more effective and user-friendly,

further improving the quality of life for millions of patients. With proper guidance and support from

healthcare professionals, nebulizers can play a crucial role in transforming asthma care, empowering

individuals to breathe easier and live healthier lives.









References:


1. Bluefish Medical. (n.d.). Nebulizer treatment. Bluefish MD. Retrieved September 29, 2024, from

2. Siddiqui, S., & Dar, A. (2015). Advantages and disadvantages of small volume nebulizers.

ResearchGate. Retrieved September 29, 2024, from

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3. Siddiqui, S., & Dar, A. (2015). Advantages and disadvantages of jet and ultrasonic nebulizers.

ResearchGate. Retrieved September 29, 2024, from

rs_tbl1_228671553

4. WebMD. (n.d.). Home nebulizer therapy. Retrieved September 29, 2024, from

5. Wikipedia. (2024, September 29). Nebulizer. In Wikipedia, The Free Encyclopedia. Retrieved

6. MedlinePlus. (2024). How to use a nebulizer. Retrieved September 29, 2024, from

7. Cleveland Clinic. (n.d.). Asthma. Retrieved September 29, 2024, from

8. Mayo Clinic. (n.d.). Asthma: Symptoms and causes. Retrieved September 29, 2024, from

9.ALL THE IMAGES DO NOT belong to me, it is taking from websites ,

that are provided in the reference section and google.

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